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Meglumine CAS 6284-40-8

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Chemical Name: Meglumine

Another Name: N-Methyl-D-glucamine

CAS No.: 6284-40-8

Molecular Formula: C7H17NO5

Molecular weight: 195.21    

Appearance: White crystalline powder

Purity: 99.0%-100.5%


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Meglumine Quick Details

Chemical Name: Meglumine

Another Name: N-Methyl-D-glucamine

CAS No.: 6284-40-8

Molecular Formula: C7H17NO5

Molecular weight: 195.21    

Meglumine Structure: Meglumine Structure

Appearance: White crystalline powder

Purity: 99.0%-100.5%

Meglumine Typical Properties

ItemSpecifications
AppearanceWhite crystalline powder
Melting point128-132℃
Residue on ignition≤0.1%
Loss on drying≤1.0%
Content99.0-100.5%
Specific optical rotation-15.7~ -17.3
Heavy metals≤20ppm
Absence of reducing substanceBlue does not change to red
Ultraviolet absorbancy degree≤0.03

Production Method

It is obtained by condensing glucose with monomethylamine and then performing catalytic hydrogenation. The anhydrous ethanol and the dried glucose were added to the reaction pot, and the dried monomethylamine gas was passed at 50 ° C. After 1.5-2 h, the solution was gradually clarified and kept at 50 ° C for 2 h to obtain a glucose methylamine solution. Then, it was added to the autoclave, and in the presence of Raney nickel, hydrogen was pressurized to 2.5 MPa, and stirred at 80-85 ° C for 1-2 h. Then, after cooling and pressure-relieving, the upper layer of meglumine ethanol solution is cooled and crystallized, and filtered to obtain crude meglumine, which is then refined to obtain a finished product.

Meglumine Usage

1. Meglumine can be used as a contrast agent and surfactant for medical use.

2. Meglumine is an amino sugar derived from sorbitol and contains an amino group, a primary hydroxyl group and a secondary hydroxyl group, which can activate nucleophilic and electrophilic structures in chemical reactions through hydrogen bonding and provided lone pair electrons, respectively. reaction. Therefore, it can not only activate the reaction components through the alkali center, but also utilize hydrogen bonding to achieve the purpose. Due to its extraordinary properties, such as low toxicity, biodegradability, physiological inertness, reusability, non-corrosiveness, and low cost, meglumine has become an important and efficient catalyst in organic synthesis, which has inspired The more researchers are interested in it.

Meglumine Packaging and Shipping

Packing: 1kg / aluminum foil bag or 25kg / drum. 

Delivery: Delivery within 2-3 days once receiving the payment

Meglumine Storage

Sealed, kept in cool and dry place. 

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